False Eyelashes

Osmosis Jones (2001) is a part animated, part live action film whose title character is Osmosis Jones, an anthropomorphic white blood cell. Unusually for this genre, the live action characters and cartoon characters never meet. more...

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The live action characters are people as they appear in the real world, and the animated characters are the cells and germs which live inside a man named Frank, whom the story concerns. A TV spinoff has been created named Ozzy & Drix, which concerns the two characters of the same name.

Plot

Frank is a slovenly zookeeper. Much to the frustration of his young daughter Shane, he eats and drinks compulsively and has no regard for germs or diseases. Early on, as a follower of the "ten second rule", to Shane's disgust, he consumes a hard-boiled egg that was covered in filth from the grass within the chimpanzees' enclosure. He had earlier been fighting for possession of the egg against one of the apes.

Inside Frank's body, another story unfolds. Osmosis Jones works as a member of Immunity, Frank's immune system, as a white blood cell. He is a rebel cop, rarely doing what his chief tells him to. Meanwhile, Mayor Phlegmming is preparing for re-election, campaigning with the promise of more junk food (much to the joy of the citizens in the Love Handle District). The Mayor's reckless policies are largely responsible for Frank's deteriorating health. However, his re-election hopes are complicated by the arrival of Thrax, a deadly virus that came in with the egg. In an attempt to cover up the severity of the situation, Phlegmming tells Frank to take a cold pill. The pill, Drix (short for Drixenol), arrives in the body and Osmosis Jones becomes his partner. Soon, they unravel Thrax's plot to masquerade as the common cold while at the same time plotting to overheat Frank's body, killing him from the inside out. Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records.

Osmosis and Drix confront Thrax in one of Frank's zits. Drix launches a grenade of medication at Thrax and his cronies, popping the skin blemish, and seemingly ending Thrax's siege. To hide the truth, Phlegmming forces Drix to leave and fires Osmosis, who insists that Thrax was more than the common cold. Osmosis' prediction rings true as Thrax was able to survive the explosion and decides to launch a one-man assault on Frank's hypothalamus.

Ozzy and Thrax fight directly. In the process, they are thrown onto one of Shane's false eyelashes, which she was wearing atop her natural ones. Ozzy is able to escape; Thrax falls into a vessel of alcohol below which destroys him. Frank is revived. Phlemming loses position as mayor and is finally ejected from the body via its rectum.

Interlaced with the main plot are several live action sequences that detail Frank's troublesome relationship with Shane outside the body. Her mother died at an early age, and we might speculate Frank has deteriorated as a result of depression caused by attachment. Frank humiliated Shane's teacher, Mrs. Boyd, during a science fair, in which after he ate another student's oyster experiment. Ozzy, patrolling the stomach at the time saw a nasty germ that had come along with the swallowed oysters and pressed the "puke" button. Mrs. Boyd is humiliated again later on in the film, when the popped blemish landed on her lip. Shane is ashamed of her father. Seeing him facing a terminal virus creates an epiphany in both of them. Frank needs to start caring for his body, and Shane learns to stop blaming Frank's apathy for her mother's death.

Read more at Wikipedia.org